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Structural basis to stabilize the domain motion of BARD1-ARD BRCT by CstF50
BRCA1 associated ring domain protein 1(BARD1) is a tumor suppressor protein having a wide role in cellular processes like cell-cycle checkpoint, DNA damage repair and maintenance of genomic integrity. Germ-line mutation Gln 564 His discovered in linker region of BARD1 leads to loss of binding to Cle...
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| Yayımlandı: | Sci Rep |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5478621/ https://ncbi.nlm.nih.gov/pubmed/28634376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03816-4 |
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