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Chronic treatment with cisplatin induces chemoresistance through the TIP60-mediated Fanconi anemia and homologous recombination repair pathways

The Fanconi anemia pathway in coordination with homologous recombination is essential to repair interstrand crosslinks (ICLs) caused by cisplatin. TIP60 belongs to the MYST family of acetyltransferases and is involved in DNA repair and regulation of gene transcription. Although the physical interact...

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Publicado no:Sci Rep
Main Authors: Su, Wen-Pin, Ho, Yen-Chih, Wu, Cheng-Kuei, Hsu, Sen-Huei, Shiu, Jia-Lin, Huang, Jheng-Cheng, Chang, Song-Bin, Chiu, Wen-Tai, Hung, Jan-Jong, Liu, Tsung-Lin, Wu, Wei-Sheng, Wu, Pei-Yu, Su, Wu-Chou, Chang, Jang-Yang, Liaw, Hungjiun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478611/
https://ncbi.nlm.nih.gov/pubmed/28634400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04223-5
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