Chronic treatment with cisplatin induces replication-dependent sister chromatid recombination to confer cisplatin-resistant phenotype in nasopharyngeal carcinoma

Cisplatin can cause intrastrand and interstrand crosslinks between purine bases and is a chemotherapeutic drug widely used to treat cancer. However, the major barrier to the efficacy of the treatment is drug resistance. Homologous recombination (HR) plays a central role in restoring stalled forks ca...

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Detalhes bibliográficos
Main Authors: Su, Wen-Pin, Hsu, Sen-Huei, Wu, Cheng-Kuei, Chang, Song-Bin, Lin, Yi-Ju, Yang, Wen-Bin, Hung, Jan-Jong, Chiu, Wen-Tai, Tzeng, Shun-Fen, Tseng, Yau-Lin, Chang, Jang-Yang, Su, Wu-Chou, Liaw, Hungjiun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171633/
https://ncbi.nlm.nih.gov/pubmed/25051366
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