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Enthalpy of helix–coil transition: Missing link in rationalizing the thermodynamics of helix-forming propensities of the amino acid residues
It is known that different amino acid residues have effects on the thermodynamic stability of an α-helix. The underlying mechanism for the thermodynamic helical propensity is not well understood. The major accepted hypothesis is the difference in the side-chain configurational entropy loss upon heli...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC547846/ https://ncbi.nlm.nih.gov/pubmed/15671166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408004102 |
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