Extracellular deoxyribonuclease made by group A Streptococcus assists pathogenesis by enhancing evasion of the innate immune response

Many pathogenic bacteria produce extracellular DNase, but the benefit of this enzymatic activity is not understood. For example, all strains of the human bacterial pathogen group A Streptococcus (GAS) produce at least one extracellular DNase, and most strains make several distinct enzymes. Despite s...

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Hlavní autoři: Sumby, Paul, Barbian, Kent D., Gardner, Donald J., Whitney, Adeline R., Welty, Diane M., Long, R. Daniel, Bailey, John R., Parnell, Michael J., Hoe, Nancy P., Adams, Gerald G., DeLeo, Frank R., Musser, James M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC547841/
https://ncbi.nlm.nih.gov/pubmed/15668390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406641102
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