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Herpesvirus orthologues of CD200 bind host CD200R but not related activating receptors

Several herpesviruses have acquired the gene for the CD200 membrane protein from their hosts and can downregulate myeloid activity through interaction of this viral CD200 orthologue with the host receptor for CD200, namely CD200R, which can give inhibitory signals. This receptor is a ‘paired recepto...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Gen Virol
Hauptverfasser: Kwong, Lai Shan, Akkaya, Munir, Barclay, A. Neil, Hatherley, Deborah
Format: Artigo
Sprache:Inglês
Veröffentlicht: Microbiology Society 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478174/
https://ncbi.nlm.nih.gov/pubmed/26538068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000335
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