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Herpesvirus orthologues of CD200 bind host CD200R but not related activating receptors

Several herpesviruses have acquired the gene for the CD200 membrane protein from their hosts and can downregulate myeloid activity through interaction of this viral CD200 orthologue with the host receptor for CD200, namely CD200R, which can give inhibitory signals. This receptor is a ‘paired recepto...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Kwong, Lai Shan, Akkaya, Munir, Barclay, A. Neil, Hatherley, Deborah
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478174/
https://ncbi.nlm.nih.gov/pubmed/26538068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000335
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