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Probing the Catalytic Charge-Relay System in Alanine Racemase with Genetically Encoded Histidine Mimetics
Histidine is a unique amino acid with an imidazole side chain in which both of the nitrogen atoms are capable of serving as a proton donor and proton acceptor in hydrogen bonding interactions. In order to probe the functional role of histidine involved in hydrogen bonding networks, fine-tuning the h...
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| Veröffentlicht in: | ACS Chem Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5478170/ https://ncbi.nlm.nih.gov/pubmed/27978711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00940 |
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