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Probing the Catalytic Charge-Relay System in Alanine Racemase with Genetically Encoded Histidine Mimetics

Histidine is a unique amino acid with an imidazole side chain in which both of the nitrogen atoms are capable of serving as a proton donor and proton acceptor in hydrogen bonding interactions. In order to probe the functional role of histidine involved in hydrogen bonding networks, fine-tuning the h...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Sharma, Vangmayee, Wang, Yane-Shih, Liu, Wenshe R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478170/
https://ncbi.nlm.nih.gov/pubmed/27978711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00940
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