Over-expressing the soluble gp130-Fc does not ameliorate methionine and choline deficient diet-induced non alcoholic steatohepatitis in mice

Non-alcoholic steatohepatitis (NASH) is a liver disease with the potential to lead to cirrhosis and hepatocellular carcinoma. Interleukin-6 (IL-6) has been implicated in the pathogenesis of NASH, with the so-called IL-6 ‘trans-signaling’ cascade being responsible for the pro-inflammatory actions of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kammoun, Helene L., Allen, Tamara Louise, Henstridge, Darren Colin, Kraakman, Michael James, Peijs, Lone, Rose-John, Stefan, Febbraio, Mark Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478123/
https://ncbi.nlm.nih.gov/pubmed/28632778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179099
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