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Clinical development of fenretinide as an antineoplastic drug: Pharmacology perspectives
Fenretinide (4-HPR) is a synthetic retinoid that has cytotoxic activity against cancer cells. Despite substantial in vitro cytotoxicity, response rates in early clinical trials with 4-HPR have been less than anticipated, likely due to the low bioavailability of the initial oral capsule formulation....
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| Pubblicato in: | Exp Biol Med (Maywood) |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
SAGE Publications
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5478002/ https://ncbi.nlm.nih.gov/pubmed/28429653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370217706952 |
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