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Chronic antidepressant administration decreases the expression of tyrosine hydroxylase in the rat locus coeruleus.

Regulation of tyrosine hydroxylase expression by antidepressant treatments was investigated in the locus coeruleus (LC), the major noradrenergic nucleus in brain. Rats were treated chronically with various antidepressants, and tyrosine hydroxylase levels were measured in the LC by immunoblot analysi...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Nestler, E J, McMahon, A, Sabban, E L, Tallman, J F, Duman, R S
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1990
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54779/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1977162/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.19.7522
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