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Chronic antidepressant administration decreases the expression of tyrosine hydroxylase in the rat locus coeruleus.

Regulation of tyrosine hydroxylase expression by antidepressant treatments was investigated in the locus coeruleus (LC), the major noradrenergic nucleus in brain. Rats were treated chronically with various antidepressants, and tyrosine hydroxylase levels were measured in the LC by immunoblot analysi...

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Detalhes bibliográficos
Main Authors: Nestler, E J, McMahon, A, Sabban, E L, Tallman, J F, Duman, R S
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC54779/
https://ncbi.nlm.nih.gov/pubmed/1977162
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