Long-term observation reveals high-frequency engraftment of human acute myeloid leukemia in immunodeficient mice

Repopulation of immunodeficient mice remains the primary method for functional assessment of human acute myeloid leukemia. Published data report engraftment in ~40–66% of cases, mostly of intermediate- or poor-risk subtypes. Here we report that extending follow-up beyond the standard analysis endpoi...

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Pubblicato in:Haematologica
Autori principali: Paczulla, Anna M., Dirnhofer, Stephan, Konantz, Martina, Medinger, Michael, Salih, Helmut R., Rothfelder, Kathrin, Tsakiris, Dimitrios A., Passweg, Jakob R., Lundberg, Pontus, Lengerke, Claudia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2017
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477604/
https://ncbi.nlm.nih.gov/pubmed/28183848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.153528
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