Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion

Patients with acute myeloid leukaemia (AML) often achieve remission after therapy, but sub-sequently die of relapse(1) that is driven by chemotherapy-resistant leukaemic stem cells (LSCs)(2,3). LSCs are defined by their capacity to initiate leukaemia in immunocompromised mice(4). However, this precl...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Nature
Glavni autori: Paczulla, Anna M., Rothfelder, Kathrin, Raffel, Simon, Konantz, Martina, Steinbacher, Julia, Wang, Hui, Tandler, Claudia, Mbarga, Marcelle, Schaefer, Thorsten, Falcone, Mattia, Nievergall, Eva, Dörfel, Daniela, Hanns, Pauline, Passweg, Jakob R., Lutz, Christoph, Schwaller, Juerg, Zeiser, Robert, Blazar, Bruce R., Caligiuri, Michael A., Dirnhofer, Stephan, Lundberg, Pontus, Kanz, Lothar, Quintanilla-Martinez, Leticia, Steinle, Alexander, Trumpp, Andreas, Salih, Helmut R., Lengerke, Claudia
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934414/
https://ncbi.nlm.nih.gov/pubmed/31316209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1410-1
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items