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Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion
Patients with acute myeloid leukaemia (AML) often achieve remission after therapy, but sub-sequently die of relapse(1) that is driven by chemotherapy-resistant leukaemic stem cells (LSCs)(2,3). LSCs are defined by their capacity to initiate leukaemia in immunocompromised mice(4). However, this precl...
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| Izdano u: | Nature |
|---|---|
| Glavni autori: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6934414/ https://ncbi.nlm.nih.gov/pubmed/31316209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1410-1 |
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