Coordination of Myeloid Differentiation with Reduced Cell Cycle Progression by PU.1 Induction of MicroRNAs Targeting Cell Cycle Regulators and Lipid Anabolism

During macrophage development, myeloid progenitor cells undergo terminal differentiation coordinated with reduced cell cycle progression. Differentiation of macrophages from myeloid progenitors is accompanied by increased expression of the E26 transformation-specific transcription factor PU.1. Reduc...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Solomon, Lauren A., Podder, Shreya, He, Jessica, Jackson-Chornenki, Nicholas L., Gibson, Kristen, Ziliotto, Rachel G., Rhee, Jess, DeKoter, Rodney P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477546/
https://ncbi.nlm.nih.gov/pubmed/28223367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00013-17
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