Optogenetic control of RhoA reveals zyxin-mediated elasticity of stress fibres

Cytoskeletal mechanics regulates cell morphodynamics and many physiological processes. While contractility is known to be largely RhoA-dependent, the process by which localized biochemical signals are translated into cell-level responses is poorly understood. Here we combine optogenetic control of R...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Oakes, Patrick W., Wagner, Elizabeth, Brand, Christoph A., Probst, Dimitri, Linke, Marco, Schwarz, Ulrich S., Glotzer, Michael, Gardel, Margaret L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477492/
https://ncbi.nlm.nih.gov/pubmed/28604737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15817
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