The albumin-exendin-4 recombinant protein E2HSA improves glycemic control and β-cell function in spontaneous diabetic KKAy mice

BACKGROUND: E2HSA is a genetic fusion protein that consists of two tandem exendin-4 molecules that are covalently bonded to recombinant human serum albumin via a peptide linker. Previous studies have demonstrated that E2HSA significantly decreased blood glucose levels, improved β-cell function and p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Pharmacol Toxicol
Prif Awduron: Li, Caina, Hou, Shaocong, Liu, Shuainan, Huan, Yi, Sun, Sujuan, Liu, Quan, Shen, Zhufang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477380/
https://ncbi.nlm.nih.gov/pubmed/28629388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-017-0143-8
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