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The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense
Microbial pattern molecules in the intestine play immunoregulatory roles via diverse pattern recognition receptors. However, the role of the cytosolic DNA sensor AIM2 in the maintenance of intestinal homeostasis is unknown. Here, we show that Aim2(−/−) mice are highly susceptible to dextran sodium s...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5477202/ https://ncbi.nlm.nih.gov/pubmed/26655906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.040 |
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