Imaging of α(v)β(3) integrin expression in experimental myocardial ischemia with [(68)Ga]NODAGA-RGD positron emission tomography

BACKGROUND: Radiolabeled RGD peptides detect α(v)β(3) integrin expression associated with angiogenesis and extracellular matrix remodeling after myocardial infarction. We studied whether cardiac positron emission tomography (PET) with [(68)Ga]NODAGA-RGD detects increased α(v)β(3) integrin expression...

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Published in:J Transl Med
Main Authors: Grönman, Maria, Tarkia, Miikka, Kiviniemi, Tuomas, Halonen, Paavo, Kuivanen, Antti, Savunen, Timo, Tolvanen, Tuula, Teuho, Jarmo, Käkelä, Meeri, Metsälä, Olli, Pietilä, Mikko, Saukko, Pekka, Ylä-Herttuala, Seppo, Knuuti, Juhani, Roivainen, Anne, Saraste, Antti
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477135/
https://ncbi.nlm.nih.gov/pubmed/28629432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1245-1
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