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Transcriptomic profiles of aging in naïve and memory CD4(+) cells from mice

BACKGROUND: CD4+ T cells can be broadly divided into naïve and memory subsets, each of which are differentially impaired by the aging process. It is unclear if and how these differences are reflected at the transcriptomic level. We performed microarray profiling on RNA derived from naïve (CD44(low))...

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Detalhes bibliográficos
Publicado no:Immun Ageing
Main Authors: Taylor, Jackson, Reynolds, Lindsay, Hou, Li, Lohman, Kurt, Cui, Wei, Kritchevsky, Stephen, McCall, Charles, Liu, Yongmei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477126/
https://ncbi.nlm.nih.gov/pubmed/28642803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-017-0092-5
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