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Conjugating a groove-binding motif to an Ir(iii) complex for the enhancement of G-quadruplex probe behavior

In this study, the reported G-quadruplex groove binder benzo[d,e]isoquinoline was linked to a cyclometallated Ir(iii) complex to generate a highly selective DNA probe 1 that retains the favorable photophysical properties of the parent complex. The linked complex 1 showed advantages of both parent co...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Wang, Modi, Mao, Zhifeng, Kang, Tian-Shu, Wong, Chun-Yuen, Mergny, Jean-Louis, Leung, Chung-Hang, Ma, Dik-Lung
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477052/
https://ncbi.nlm.nih.gov/pubmed/28660021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00001k
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