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Sulfur-Switch Ugi Reaction for Macrocyclic Disulfide-Bridged Peptidomimetics
[Image: see text] A general strategy is introduced for the efficient synthetic access of disulfide linked artificial macrocycles via a Ugi four-component reaction (U4CR) followed by oxidative cyclization. The double-mercapto input is proposed for use in the Ugi reaction, thereby yielding all six top...
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| Foilsithe in: | Org Lett |
|---|---|
| Main Authors: | , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American
Chemical Society
2017
|
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5477004/ https://ncbi.nlm.nih.gov/pubmed/28581763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b01324 |
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