Apolipoprotein E - A Multifunctional Protein with Implications in Various Pathologies as a Result of Its Structural Features

Apolipoprotein E (apoE), a 34 kDa glycoprotein, mediates hepatic and extrahepatic uptake of plasma lipoproteins and cholesterol efflux from lipid-laden macrophages. In humans, three structural different apoE isoforms occur, with subsequent functional changes and pathological consequences. Here, we r...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Comput Struct Biotechnol J
Hlavní autoři: Tudorache, Irina Florina, Trusca, Violeta Georgeta, Gafencu, Anca Violeta
Médium: Artigo
Jazyk:Inglês
Vydáno: Research Network of Computational and Structural Biotechnology 2017
Témata:
Mini Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476973/
https://ncbi.nlm.nih.gov/pubmed/28660014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2017.05.003
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky