Nutrients required for phospholipid synthesis are lower in blood and cerebrospinal fluid in mild cognitive impairment and Alzheimer's disease dementia

INTRODUCTION: Synaptic membrane formation depends on nutrients that fuel metabolic pathways for the synthesis of constituent phospholipids. Consequently, insufficient availability of such nutrients may restrict membrane formation and contribute to synaptic dysfunction in Alzheimer's disease (AD...

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發表在:Alzheimers Dement (Amst)
Main Authors: van Wijk, Nick, Slot, Rosalinde E.R., Duits, Flora H., Strik, Marieke, Biesheuvel, Egbert, Sijben, John W.C., Blankenstein, Marinus A., Bierau, Jörgen, van der Flier, Wiesje M., Scheltens, Philip, Teunissen, Charlotte E.
格式: Artigo
語言:Inglês
出版: Elsevier 2017
主題:
Blood Based Biomarkers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476966/
https://ncbi.nlm.nih.gov/pubmed/28653034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2017.04.005
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