Nutrients required for phospholipid synthesis are lower in blood and cerebrospinal fluid in mild cognitive impairment and Alzheimer's disease dementia

INTRODUCTION: Synaptic membrane formation depends on nutrients that fuel metabolic pathways for the synthesis of constituent phospholipids. Consequently, insufficient availability of such nutrients may restrict membrane formation and contribute to synaptic dysfunction in Alzheimer's disease (AD...

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Bibliografiske detaljer
Udgivet i:Alzheimers Dement (Amst)
Main Authors: van Wijk, Nick, Slot, Rosalinde E.R., Duits, Flora H., Strik, Marieke, Biesheuvel, Egbert, Sijben, John W.C., Blankenstein, Marinus A., Bierau, Jörgen, van der Flier, Wiesje M., Scheltens, Philip, Teunissen, Charlotte E.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Blood Based Biomarkers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476966/
https://ncbi.nlm.nih.gov/pubmed/28653034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2017.04.005
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