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Nickel-Catalyzed Reduction of Secondary and Tertiary Amides

The nickel-catalyzed reduction of secondary and tertiary amides to give amine products is reported. The transformation is tolerant of extensive variation with respect to the amide substrate, proceeds in the presence of esters and epimerizable stereocenters, and can be used to achieve the reduction o...

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Bibliografiske detaljer
Udgivet i:Org Lett
Main Authors: Simmons, Bryan J., Hoffmann, Marie, Hwang, Jaeyeon, Jackl, Moritz K., Garg, Neil K.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476940/
https://ncbi.nlm.nih.gov/pubmed/28339212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b00683
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