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Nickel-Catalyzed Conversion of Amides to Carboxylic Acids
We report the conversion of amides to carboxylic acids using nonprecious metal catalysis. The methodology strategically employs a nickel-catalyzed esterification using 2-(trimethylsilyl)-ethanol, followed by a fluoride-mediated deprotection in a single-pot operation. This approach circumvents cataly...
Enregistré dans:
| Publié dans: | Org Lett |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7184625/ https://ncbi.nlm.nih.gov/pubmed/32208664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c00885 |
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