Inactivation of the Thymidylate Synthase thyA in Non-typeable Haemophilus influenzae Modulates Antibiotic Resistance and Has a Strong Impact on Its Interplay with the Host Airways

Antibacterial treatment with cotrimoxazol (TxS), a combination of trimethoprim and sulfamethoxazole, generates resistance by, among others, acquisition of thymidine auxotrophy associated with mutations in the thymidylate synthase gene thyA, which can modify the biology of infection. The opportunisti...

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Detaylı Bibliyografya
Yayımlandı:Front Cell Infect Microbiol
Asıl Yazarlar: Rodríguez-Arce, Irene, Martí, Sara, Euba, Begoña, Fernández-Calvet, Ariadna, Moleres, Javier, López-López, Nahikari, Barberán, Montserrat, Ramos-Vivas, José, Tubau, Fe, Losa, Carmen, Ardanuy, Carmen, Leiva, José, Yuste, José E., Garmendia, Junkal
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2017
Konular:
Microbiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476696/
https://ncbi.nlm.nih.gov/pubmed/28676846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00266
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