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Chronic treatment with a smart antioxidative nanoparticle for inhibition of amyloid plaque propagation in Tg2576 mouse model of Alzheimer’s disease

The present study aimed to assess whether our newly developed redox nanoparticle (RNP(N)) that has antioxidant potential decreases Aβ levels or prevents Aβ aggregation associated with oxidative stress. The transgenic Tg2576 Alzheimer’s disease (AD) mice were used to investigate the effect of chronic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Boonruamkaew, Phetcharat, Chonpathompikunlert, Pennapa, Vong, Long Binh, Sakaue, Sho, Tomidokoro, Yasushi, Ishii, Kazuhiro, Tamaoka, Akira, Nagasaki, Yukio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476667/
https://ncbi.nlm.nih.gov/pubmed/28630497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03411-7
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