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Dense-Core Plaques in Tg2576 and PSAPP Mouse Models of Alzheimer’s Disease Are Centered on Vessel Walls

Occurrence of amyloid β (Aβ) dense-core plaques in the brain is one of the chief hallmarks of Alzheimer’s disease (AD). It is not yet clear what factors are responsible for the aggregation of Aβ in the formation of these plaques. Using Tg2576 and PSAPP mouse models that exhibit age-related developme...

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Detalhes bibliográficos
Main Authors: Kumar-Singh, Samir, Pirici, Daniel, McGowan, Eileen, Serneels, Sally, Ceuterick, Chantal, Hardy, John, Duff, Karen, Dickson, Dennis, Van Broeckhoven, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1603563/
https://ncbi.nlm.nih.gov/pubmed/16049337
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