Acute administration of catalase targeted to ICAM-1 attenuates neuropathology in experimental traumatic brain injury

Traumatic brain injury (TBI) contributes to one third of injury related deaths in the US. Treatment strategies for TBI are supportive, and the pathophysiology is not fully understood. Secondary mechanisms of injury in TBI, such as oxidative stress and inflammation, are points at which intervention m...

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Опубликовано в: :Sci Rep
Главные авторы: Lutton, Evan M., Razmpour, Roshanak, Andrews, Allison M., Cannella, Lee Anne, Son, Young-Jin, Shuvaev, Vladimir V., Muzykantov, Vladimir R., Ramirez, Servio H.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476649/
https://ncbi.nlm.nih.gov/pubmed/28630485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03309-4
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