Acute administration of catalase targeted to ICAM-1 attenuates neuropathology in experimental traumatic brain injury

Traumatic brain injury (TBI) contributes to one third of injury related deaths in the US. Treatment strategies for TBI are supportive, and the pathophysiology is not fully understood. Secondary mechanisms of injury in TBI, such as oxidative stress and inflammation, are points at which intervention m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lutton, Evan M., Razmpour, Roshanak, Andrews, Allison M., Cannella, Lee Anne, Son, Young-Jin, Shuvaev, Vladimir V., Muzykantov, Vladimir R., Ramirez, Servio H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476649/
https://ncbi.nlm.nih.gov/pubmed/28630485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03309-4
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