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Improving Prediction of Helix-Helix Packing in Membrane Proteins Using Predicted Contact Numbers as Restraints

One of the challenging problems in computational prediction of tertiary structure of helical membrane proteins (HMPs) is the determination of rotation of α-helices around the helix normal. Incorrect prediction of rotation of α-helices around the helix normal substantially disrupts native residue–res...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proteins
Prif Awduron: Li, Bian, Mendenhall, Jeffrey, Nguyen, Elizabeth Dong, Weiner, Brian E., Fischer, Axel W., Meiler, Jens
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476507/
https://ncbi.nlm.nih.gov/pubmed/28263405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25281
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