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The design and synthesis of an α-Gal trisaccharide epitope that provides a highly specific anti-Gal immune response
Carbohydrate antigens displaying Galα(1,3)Gal epitopes are recognized by naturally occurring antibodies in humans. These anti-Gal antibodies comprise up to 1% of serum IgG and has been viewed as detrimental as they are responsible for hyperacute organ rejections. In order to model this condition, α(...
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| Gepubliceerd in: | Org Biomol Chem |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5476458/ https://ncbi.nlm.nih.gov/pubmed/28294277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob00448f |
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