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Survival, bacterial clearance and thrombocytopenia are improved in polymicrobial sepsis by targeting nuclear transport shuttles

The rising tide of sepsis, a leading cause of death in the US and globally, is not adequately controlled by current antimicrobial therapies and supportive measures, thereby requiring new adjunctive treatments. Severe microvascular injury and multiple organ failure in sepsis are attributed to a “geno...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Veach, Ruth Ann, Liu, Yan, Zienkiewicz, Jozef, Wylezinski, Lukasz S., Boyd, Kelli L., Wynn, James L., Hawiger, Jacek
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476269/
https://ncbi.nlm.nih.gov/pubmed/28628637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179468
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