Survival, bacterial clearance and thrombocytopenia are improved in polymicrobial sepsis by targeting nuclear transport shuttles

The rising tide of sepsis, a leading cause of death in the US and globally, is not adequately controlled by current antimicrobial therapies and supportive measures, thereby requiring new adjunctive treatments. Severe microvascular injury and multiple organ failure in sepsis are attributed to a “geno...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Veach, Ruth Ann, Liu, Yan, Zienkiewicz, Jozef, Wylezinski, Lukasz S., Boyd, Kelli L., Wynn, James L., Hawiger, Jacek
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476269/
https://ncbi.nlm.nih.gov/pubmed/28628637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179468
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