Survival, bacterial clearance and thrombocytopenia are improved in polymicrobial sepsis by targeting nuclear transport shuttles

The rising tide of sepsis, a leading cause of death in the US and globally, is not adequately controlled by current antimicrobial therapies and supportive measures, thereby requiring new adjunctive treatments. Severe microvascular injury and multiple organ failure in sepsis are attributed to a “geno...

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Vydáno v:PLoS One
Hlavní autoři: Veach, Ruth Ann, Liu, Yan, Zienkiewicz, Jozef, Wylezinski, Lukasz S., Boyd, Kelli L., Wynn, James L., Hawiger, Jacek
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476269/
https://ncbi.nlm.nih.gov/pubmed/28628637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179468
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