تحميل...
Computational explanation for bioactivation mechanism of targeted anticancer agents mediated by cytochrome P450s: A case of Erlotinib
EGFR inhibitors, even with therapeutics superiorities in anticancer, can cause idiosyncratic pulmonary and hepatic toxicities that are associated with the reactive electrophile bioactivated by Cytochrome P450s (P450s). Until now, neither has the electrophilic intermediate been caught experimentally,...
محفوظ في:
| الحاوية / القاعدة: | PLoS One |
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| المؤلفون الرئيسيون: | , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Public Library of Science
2017
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5476264/ https://ncbi.nlm.nih.gov/pubmed/28628631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179333 |
| الوسوم: |
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