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116.3 Discovery and Evaluation of Nonnitrocatechol COMT Inhibitors for Treatment of Psychiatric Conditions
Background: Catechol-O-methyltransferase (COMT) plays an important role in the termination of dopamine signaling in brain regions such as the prefrontal cortex and hippocampus, making it an important regulator of a number of cognitive and behavioral processes. Therefore, brain-penetrating inhibitors...
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| Publicado no: | Schizophr Bull |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475774/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.165 |
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