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177.1 Cortical Hypodopaminergia Versus Striatal Hyperdopaminergia Revisited in an NMDAR Hypofunction Model of Schizophrenia

Background: Clinical evidence from in vivo PET imaging demonstrates an increase in psychostimulant-induced dopamine (DA) release in the striatum of patients with schizophrenia. A recent PET imaging study also showed a deficit in amphetamine-induced DA release in PFC in schizophrenia (Slifstein et al...

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Dades bibliogràfiques
Publicat a:Schizophr Bull
Autor principal: Nakao, Kazuhito
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475706/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.248
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