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131. Polygenic Risk Profile Scores Predict Cognitive Performance in Many Schizophrenia Cases but for Individuals With a Large Premorbid/Current IQ Difference, They Don’t

Background: Generalized cognitive impairment is a core characteristic of schizophrenia. Risk profile scores (RPS) summarize an individual’s risk for developing schizophrenia based on numerous common genetic variants associated with the condition. Various work points to overlap in cognitive and schiz...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: Dickinson, Dwight, Zaidman, Sofia, Giangrande, Evan, Weinberger, Daniel, Berman, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475649/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.189
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