TRTH-14. TARGETING CHK1 AND AKT CROSSTALK IN MUTANT P53 PEDIATRIC GLIOBLASTOMA

Pediatric high-grade gliomas are the most common and universally deadly form of CNS malignancy. Combination therapies that exploit the DNA Damage Response (DDR) offer avenues to improve clinical outcome in patients with pediatric glioblastoma (GBM). We hypothesize that dual inhibition of the prosurv...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Stamatkin, Chris, Dave, Nimita, Shannon, Harlan, Bailey, Barbara, Ding, Jixin, Saadatzadeh, Reza, Murray, Mary, Cohen-Gadol, Aaron, Renbarger, Jamie, Pollok, Karen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475199/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.226
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