TRTH-13. BMI1 IS A THERAPEUTIC TARGET IN RECURRENT MEDULLOBLASTOMA

Bmi1 is a master regulatory stem cell self-renewal gene and epigenetic regulator that presents a downstream target of developmental pathways active during the genesis of the childhood brain tumor medulloblastoma (MB). Here, we describe Bmi1 as a novel therapeutic target for the treatment of recurren...

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Vydáno v:Neuro Oncol
Hlavní autoři: Bakhshinyan, David, Garg, Neha, Manoranjan, Branavan, Venugopal, Chitra, Hallett, Robin, Wang, Xin, Kameda-smith, Michelle, Adile, Ashley, Ramaswamy, Vijay, Davis, Thomas, Weetall, Marla, Moon, Young-choon, Mitra, Siddhartha, Cho, Yoon-Jae, Taylor, Michael, Singh, Sheila
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475198/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.225
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