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TMOD-02. PEDIATRIC MEDULLOBLASTOMA XENOGRAFT GROWTH LOCATION TRANSFORMS TRANSCRIPTOMIC BUT NOT PHENOTYPIC PROFILES AND ALTERS SENSITIVITY TO RADIATION
Patient-derived xenograft models maintained in immunodeficient mice provide a powerful preclinical tool for testing oncologic therapies. Xenograft response to treatment informs which agents advance to human clinical trials. Frequently, pediatric brain tumor models are grown and tested heterotopicall...
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Publicado no: | Neuro Oncol |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475177/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.202 |
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