Pediatric medulloblastoma xenografts including molecular subgroup 3 and CD133+ and CD15+ cells are sensitive to killing by oncolytic herpes simplex viruses

BACKGROUND: Childhood medulloblastoma is associated with significant morbidity and mortality that is compounded by neurotoxicity for the developing brain caused by current therapies, including surgery, craniospinal radiation, and chemotherapy. Innate therapeutic resistance of some aggressive pediatr...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Friedman, Gregory K., Moore, Blake P., Nan, Li, Kelly, Virginia M., Etminan, Tina, Langford, Catherine P., Xu, Hui, Han, Xiaosi, Markert, James M., Beierle, Elizabeth A., Gillespie, G. Yancey
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724175/
https://ncbi.nlm.nih.gov/pubmed/26188016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov123
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