Pediatric medulloblastoma xenografts including molecular subgroup 3 and CD133+ and CD15+ cells are sensitive to killing by oncolytic herpes simplex viruses

BACKGROUND: Childhood medulloblastoma is associated with significant morbidity and mortality that is compounded by neurotoxicity for the developing brain caused by current therapies, including surgery, craniospinal radiation, and chemotherapy. Innate therapeutic resistance of some aggressive pediatr...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Friedman, Gregory K., Moore, Blake P., Nan, Li, Kelly, Virginia M., Etminan, Tina, Langford, Catherine P., Xu, Hui, Han, Xiaosi, Markert, James M., Beierle, Elizabeth A., Gillespie, G. Yancey
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724175/
https://ncbi.nlm.nih.gov/pubmed/26188016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov123
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