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MEDU-37. CHOLESTEROL BIOSYNTHESIS REPRESENTS A NOVEL THERAPEUTIC TARGET FOR THE SONIC HEDGEHOG TYPE OF MEDULLOBLASTOMA
Aberrant activation of Sonic hedgehog (Shh) signaling leads to formation of numerous malignancies, including the most common pediatric brain tumor - medulloblastoma (MB). Despite recent advances in MB treatment, a significant proportion of patients still succumb to this disease. MB survivors often s...
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| Izdano u: | Neuro Oncol |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475155/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.187 |
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