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IMMU-21. CHARACTERIZING IDO1 AND ITS THERAPEUTIC POTENTIAL IN PEDIATRIC CENTRAL NERVOUS SYSTEM TUMORS
BACKGROUND: Indoleamine 2,3 dioxygenase 1 (IDO1) and tryptophan dioxygenase (TDO2) are tryptophan catabolic enzymes that are implicated in immunosuppression in cancer. Both enzymes have been correlated with decreased overall survival in adult patients with glioma. We hypothesized that pediatric CNS...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475113/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.131 |
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