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IMMU-04. HIGH FREQUENCY OF PROGRAMMED DEATH LIGAND 1 EXPRESSION IN PEDIATRIC CENTRAL NERVOUS SYSTEM TUMORS
Tumors escape immune surveillance by activating the inhibitory checkpoint programmed death 1 (PD-1)/programmed death ligand 1 (PDL-1) pathway to attenuate T cell responses and render them functionally exhausted. Antibodies targeting the PD-1/PDL-1 immune checkpoint pathway rescue anti-tumor function...
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| Publié dans: | Neuro Oncol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475079/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.115 |
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