Low Frequency of Programmed Death Ligand 1 Expression in Pediatric Cancers

Programmed death 1 (PD‐1)/programmed death ligand 1 (PD‐L1) pathway blockade has become a promising therapeutic target in adult cancers. We evaluated PD‐L1 expression and tumor‐infiltrating CD8(+) T cells in formalin‐fixed, paraffin‐embedded tumor specimens from 53 untreated pediatric patients with...

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Publicado en:Pediatr Blood Cancer
Autores principales: Aoki, Takahiro, Hino, Moeko, Koh, Katsuyoshi, Kyushiki, Masashi, Kishimoto, Hiroshi, Arakawa, Yuki, Hanada, Ryoji, Kawashima, Hiroshi, Kurihara, Jun, Shimojo, Naoki, Motohashi, Shinichiro
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
Materias:
Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074238/
https://ncbi.nlm.nih.gov/pubmed/27135656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.26018
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