DIPG-43. PROLONGED CONVECTION-ENHANCED DELIVERY IN THE PONS WITH SN-38 LOADED NANOPARTICLES AND IRINOTECAN

INTRODUCTION: Inadequate drug delivery due to an intact blood-brain barrier (BBB) could explain part of the resistance to chemotherapeutic agents in diffuse intrinsic pontine glioma (DIPG). Convection-enhanced delivery (CED) is an alternative mode of local delivery and irinotecan, and its active com...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Sewing, A Charlotte, Olaciregui, Nagore G, Monterrubio, Carles, Kaspers, Gertjan, Mora, Jaume, Hulleman, Esther, Carcaboso, Angel M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475026/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.058
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