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Astrocytic glycogen-derived lactate fuels the brain during exhaustive exercise to maintain endurance capacity

Brain glycogen stored in astrocytes provides lactate as an energy source to neurons through monocarboxylate transporters (MCTs) to maintain neuronal functions such as hippocampus-regulated memory formation. Although prolonged exhaustive exercise decreases brain glycogen, the role of this decrease an...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Matsui, Takashi, Omuro, Hideki, Liu, Yu-Fan, Soya, Mariko, Shima, Takeru, McEwen, Bruce S., Soya, Hideaki
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474817/
https://ncbi.nlm.nih.gov/pubmed/28515312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702739114
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