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Astrocytic glycogen-derived lactate fuels the brain during exhaustive exercise to maintain endurance capacity

Brain glycogen stored in astrocytes provides lactate as an energy source to neurons through monocarboxylate transporters (MCTs) to maintain neuronal functions such as hippocampus-regulated memory formation. Although prolonged exhaustive exercise decreases brain glycogen, the role of this decrease an...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Matsui, Takashi, Omuro, Hideki, Liu, Yu-Fan, Soya, Mariko, Shima, Takeru, McEwen, Bruce S., Soya, Hideaki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474817/
https://ncbi.nlm.nih.gov/pubmed/28515312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702739114
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